Myosin If (MYO1F), also designated Myosin-Ie, is considered an unconventional Myosin and is expressed in the cochlea. The MYO1F gene encoding for the 220 amino acid protein maps to chromosome 19p13.3-13.2.
Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.
Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.
Contains 1 SH3 domain.
SWISS:
O00160
Gene ID:
4542
Database links:
Entrez Gene: 4542 Human
Entrez Gene: 17916 Mouse
Entrez Gene: 314654 Rat
Omim: 60296 Human
SwissProt: O00160 Human
SwissProt: P70248 Mouse
Unigene: 465818 Human
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