G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR97 (G protein-coupled receptor 97), also known as PB99 or PGR26, is a 549 amino acid multi-pass membrane protein that contains one GPS domain and belongs to the G-protein coupled receptor 2 family. GPR97 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell.
Function:
Orphan receptor.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
SWISS:
Q86Y34
Gene ID:
54672
Database links:
Entrez Gene: 222487 Human
Entrez Gene: 54672 Mouse
Entrez Gene: 291854 Rat
SwissProt: Q86Y34 Human
SwissProt: Q8R0T6 Mouse
Unigene: 383403 Human
Unigene: 27995 Mouse
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