This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the SLCtype lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Dec 2010]
Function:
Might be a stress protein involved in the control of bacterial proliferation.
Subcellular Location:
Secreted. Found in the apical region of pancreatic acinar cells.
Tissue Specificity:
Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
Similarity:
Contains 1 SLCtype lectin domain.
SWISS:
O09037
Gene ID:
19694
Database links:
Entrez Gene: 5068 Human
Entrez Gene: 19694 mouse
Omim: 167805 Human
SwissProt: Q06141 Human
Unigene: 567312 Human
|
|
