Rabbit Anti-PERP/p53 apoptosis effector related to PMP22 antibody

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KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector rel

Cat:

SL10783R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human p53 apoptosis effector related to PMP22:101-193/193

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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PERP (PERP, TP53 Apoptosis Effector) is a Protein Coding gene. Diseases associated with PERP include Arrhythmogenic Right Ventricular Cardiomyopathy and Uveal Melanoma. Among its related pathways are Keratinization and p53 Pathway (RnD). An important paralog of this gene is TMEM47.

Function:
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.

Subcellular Location:
Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes.

Tissue Specificity:
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.

Similarity:
Belongs to the TMEM47 family.

SWISS:
Q96FX8

Gene ID:
12865

Database links:

Entrez Gene: 12865 Human

Entrez Gene: 12858 Mouse

Omim: 609301 Human

SwissProt: Q96FX8 Human

SwissProt: Q9JK95 Mouse

Unigene: 201446 Human

Unigene: 28209 Mouse

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