CQ028 may play an important role in the development of cancers in a broad range of tissues.
Function:
May play an important role in the development of cancers in a broad range of tissues.
Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the cytosol and the Golgi apparatus.
Tissue Specificity:
Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines.
Similarity:
Belongs to the hid-1 family.
SWISS:
Q8IV36
Gene ID:
283987
Database links:
Entrez Gene: 283987 Human
Omim: 605752 Human
SwissProt: Q8IV36 Human
Unigene: 11067 Human
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Paraformaldehyde-fixed, paraffin embedded (mouse stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CQ028) Polyclonal Antibody, Unconjugated (SL10951R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CQ028) Polyclonal Antibody, Unconjugated (SL10951R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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