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Home > Product > Antibody > Rabbit Anti-NEK10 antibody
FLJ32685; Never in mitosis A related kinase 10; NIMA (never in mitosis gene a) related kinase 10; NimA related protein kinase 10; Serine/threonine protein kinase Nek10. NEK10_HUMAN
Cat:
SL19194R
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human NEK10:51-150/1172
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


Nek10 is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its SLCterminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.
Predicted molecular weight: 55 kDa for Isoform 5 (and 133 kDa for Isoform 1).

Function:
NEK10 belongs to the protein kinase superfamily; Ser/Thr protein kinase family; NIMA subfamily.

Similarity:
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Contains 1 ARM repeat.
Contains 1 protein kinase domain.

SWISS:
Q6ZWH5

Gene ID:
152110

Database links:

Entrez Gene: 152110 Human

Entrez Gene: 238944 Mouse

SwissProt: Q6ZWH5 Human

SwissProt: Q3UGM2 Mouse



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