This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008]
Function:
Hydrolyzes sialylated compounds.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2D1.
Similarity:
Belongs to the glycosyl hydrolase 33 family.
Contains 2 BNR repeats.
SWISS:
Q9Y3R4
Gene ID:
4759
Database links:
Entrez Gene: 4759 Human
SwissProt: Q9Y3R4 Human
Unigene: 532681 Human
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