Rabbit Anti-ANGPTL6 antibody

Home > Product > Antibody > Rabbit Anti-ANGPTL6 antibody

ARP5; AGF; Angiopoietin like 6; Angiopoietin like Protein 6; Angiopoietin related Growth Factor; Angiopoietin related protein 5; Angiopoietin-like protein 6; Angiopoietin-related growth factor; Angiopoietin-related protein 5; Angiopoietin-related protein

Cat:

SL10970R

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human ANGPTL6:371-470/470

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

Angptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen SLCterminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract obesity by increasing energy expenditure. Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Function:
May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.

Subcellular Location:
Secreted (Probable).

Similarity:
Contains 1 fibrinogen SLCterminal domain.

SWISS:
Q8NI99

Gene ID:
83854

Database links:

Entrez Gene: 83854 Human

Entrez Gene: 70726 Mouse

Omim: 609336 Human

SwissProt: Q8NI99 Human

SwissProt: Q8R0Z6 Mouse

Unigene: 712850 Human

Unigene: 34019 Mouse

Product Feedback Wall