Rabbit Anti-NFYB antibody | Sunlong Medical

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CAAT box DNA binding protein subunit B; CBF A; CBF B; CCAAT binding transcription factor subunit A; HAP 3; HAP3; NF Y protein chain B; NF YB; NFYB; Nuclear transcription factor Y beta; Nuclear transcription factor Y subunit B; Nuclear transcrip

Cat:

SL19230R

Species Reactivity：

(predicted: Mouse,Horse,Xenopus laevis.)

Immunogen：

KLH conjugated synthetic peptide derived from human NFYB:1-100/207

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]

Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the NFYB/HAP3 subunit family.

SWISS:
P25208

Gene ID:
961

Database links:

Entrez Gene: 396205 Chicken

Entrez Gene: 614382 Cow

Entrez Gene: 961 Human

Entrez Gene: 3645 Mouse

Entrez Gene: 100157587 Pig

Entrez Gene: 25336 Rat

Entrez Gene: 399126 Xenopus laevis

Omim: 189904 Human

SwissProt: P25207 Chicken

SwissProt: Q32KW0 Cow

SwissProt: P25208 Human

SwissProt: P63139 Mouse