FLJ42609;
FLJ45833;
Zic family member 4;
ZIC4;
ZIC4_HUMAN;
Zinc family member 4 protein HZIC4;
Zinc finger protein of cerebellum 4;
Zinc finger protein of the cerebellum 4;
Zinc finger protein ZIC 4.
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009]
Function: Binds to DNA.
Subcellular Location: Nucleus.
Similarity: Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
Specific References (1) | SL19238R has been referenced in 1 publications.
[IF=2.456] Han W et al. Clinicopathologic and Prognostic Significance of the Zinc Finger of the Cerebellum Family in Invasive Breast Cancer.J Breast Cancer. 2018 Mar;21(1):51-61. IHC ; Human.
