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Rabbit Anti-NKIRAS2 antibody
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
SWISS:
Q9NYR9
Gene ID:
28511
Database links:
Entrez Gene: 509053 Cow
Entrez Gene: 28511 Human
Entrez Gene: 71966 Mouse
Entrez Gene: 287707 Rat
Omim: 604497 Human
SwissProt: Q9NYR9 Human
SwissProt: Q9CR56 Mouse
Unigene: 632252 Human
Unigene: 274734 Mouse
Unigene: 90866 Rat
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