Home > Product > Antibody > Rabbit Anti-NKIRAS2 antibody
DKFZP434N1526; I kappa B interacting Ras like protein 2; I-kappa-B-interacting Ras-like protein 2; Kappa B Ras protein 2; Kappa B-Ras protein 2; KappaB Ras2; KappaB-Ras2; KBRAS 2; KBRAS2; KBRS2_HUMAN; MGC74742; NF kappa B inhibitor interacting
Cat:
SL19265R
Species Reactivity:
(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human NKIRAS2:121-191/191
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

SWISS:
Q9NYR9

Gene ID:
28511

Database links:

Entrez Gene: 509053 Cow

Entrez Gene: 28511 Human

Entrez Gene: 71966 Mouse

Entrez Gene: 287707 Rat

Omim: 604497 Human

SwissProt: Q9NYR9 Human

SwissProt: Q9CR56 Mouse

Unigene: 632252 Human

Unigene: 274734 Mouse

Unigene: 90866 Rat



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