The NKX family of homeodomain proteins controls numerous developmental processes. Members of the NKX6 subfamily, including NKX6-3, are involved in development of the central nervous system (CNS), gastrointestinal tract, and pancreas (Alanentalo et al., 2006 [PubMed 16326147]).[supplied by OMIM, Mar 2008]
Function:
Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 homeobox DNA-binding domain.
SWISS:
A6NJ46
Gene ID:
157848
Database links:
Entrez Gene: 157848 Human
Entrez Gene: 74561 Mouse
Omim: 610772 Human
SwissProt: A6NJ46 Human
SwissProt: Q3UHX8 Mouse
Unigene: 647132 Human
Unigene: 58028 Mouse
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