Rabbit Anti-phospho-NMDAR2A (Ser1232) antibody

Home > Product > Antibody > Rabbit Anti-phospho-NMDAR2A (Ser1232) antibody

NMDAR2A (phospho S1232); p-NMDAR2A (phospho S1232); GRIN2B; Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; GRIN2A; hNR2A;

Cat:

SL19290R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Horse,Rabbit,)

Immunogen：

KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232:MR(p-S)PF

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $256.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Function:
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.

Subcellular Location:
Cell membrane. Cell junction > synapse > postsynaptic cell membrane.

Similarity:
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily.

SWISS:
Q12879

Gene ID:
2903

Database links:

Entrez Gene: 2903 Human

Entrez Gene: 14811 Mouse

Entrez Gene: 2889 Rat

Omim: 138253 Human

SwissProt: Q12879 Human

SwissProt: P35436 Mouse

SwissProt: Q00959 Rat

Unigene: 411472 Human

Unigene: 2953 Mouse

Unigene: 9710 Rat

Product Feedback Wall