Rabbit Anti-NOL12/NOP25 antibody

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C78541; dJ37E16.7; FLJ34609; MGC3731; Nol12; NOL12_HUMAN; Nop25; Nucleolar protein 12; Nucleolar protein of 25 kDa.

Cat:

SL19309R

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human NOL12/NOP25:121-213/213

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Nop25 is a 213 amino acid protein that localizes to the nucleolus and is thought to bind to 28S rRNA, possibly playing a role in the processing of rRNA molecules and in the subsequent assembly and maturation of ribosomes. The gene encoding Nop25 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Function:
May bind to 28S rRNA.

Subcellular Location:
Nucleus > nucleolus.

Similarity:
Belongs to the RRP17 family.

SWISS:
Q9UGY1

Gene ID:
79159

Database links:

Entrez Gene: 79159 Human

Entrez Gene: 97961 Mouse

Entrez Gene: 362955 Rat

SwissProt: Q9UGY1 Human

SwissProt: Q8BG17 Mouse

SwissProt: Q5D1Z3 Rat

Unigene: 632778 Human

Unigene: 157216 Mouse

Unigene: 17454 Rat

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