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Rabbit Anti-CTAGE1 antibody
Cutaneous T-cell lymphoma-associated antigen 1 (CTAGE1) is normally expressed only in testis tissue, and is found in 35% of CTCL tissues, but not in any leukemia or melanoma cell lines. The gene encoding for CTAGE1 maps to chromosome 18p11.2. CTAGE2 is a longer variant of CTAGE1 and is translated from a different open reading frame. Three other splice variants related to the major CTAGE1 and CTAGE2 variants exist, some of which are expressed only in testis, while others are expressed in a wide range of adult and fetal tissues. CTAGE1 may be an important factor in the specific immunotherapy of cutaneous T-cell lymphoma and other malignancies.
Subcellular Location:
Membrane.
Tissue Specificity:
Testis. Not found in tumor.
Similarity:
Belongs to the cTAGE family.
SWISS:
Q96RT6
Gene ID:
64693
Database links:
Entrez Gene: 64693 Human
Omim: 608856 Human
SwissProt: Q96RT6 Human
Unigene: 406709 Human
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