Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
Function:
Plays a role in targeting PPP1CA to the nucleolus.
Subcellular Location:
Nucleus > nucleolus.
Tissue Specificity:
Expressed in heart and skeletal muscle.
Similarity:
Belongs to the CWC22 family.
Contains 1 MI domain.
Contains 1 MIF4G domain.
SWISS:
Q5C9Z4
Gene ID:
64434
Database links:
Entrez Gene: 64434 Human
Omim: 611269 Human
SwissProt: Q5C9Z4 Human
Unigene: 15825 Human
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