Rabbit Anti-GTF2A1 alpha antibody

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General transcription factor IIA subunit 1; General transcription factor IIA1; Glucose regulated protein 58kD pseudogene; gtf2a1; TF2A1; TF2AA_HUMAN; TFIIA 42; TFIIA alpha p55; TFIIA alpha p55, isoform 1; TFIIA p35 subunit; TFIIA-42; TFIIAL; T

Cat:

SL16410R

Species Reactivity：

(predicted: Human,Mouse,Rat,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human GTF2A1 alpha:1-100/376

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 36660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]

Function:
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

Subcellular Location:
Nucleus.

Post-translational modifications:
The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation.

Similarity:
Belongs to the TFIIA subunit 1 family.

SWISS:
P52655

Gene ID:
2957

Database links:

Entrez Gene: 2957 Human

Entrez Gene: 8722 Mouse

Entrez Gene: 83830 Rat

Omim: 600520 Human

SwissProt: P52655 Human

SwissProt: Q99PM3 Mouse

SwissProt: O08949 Rat

Unigene: 592334 Human

Unigene: 275728 Mouse

Unigene: 432242 Mouse

Unigene: 44436 Rat

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