Rabbit Anti-NPL/N-acetylneuraminate lyase antibody

Home > Product > Antibody > Rabbit Anti-NPL/N-acetylneuraminate lyase antibody

0610033B02Rik; C112; C1orf13; Dihydrodipicolinate synthase; Dihydrodipicolinate synthetase homolog 1; MGC149582; MGC61869; N-acetylneuraminate lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NAL; NALase; NPL; NPL_

Cat:

SL19332R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human NPL/N-acetylneuraminate lyase:161-260/320

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Function:
Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Isoform 2 is expressed in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte.

Similarity:
Belongs to the DHDPS family. NanA subfamily.

SWISS:
Q9BXD5

Gene ID:
80896

Database links:

Entrez Gene: 80896 Human

Omim: 611412 Human

SwissProt: Q9BXD5 Human

Unigene: 496969 Human

Product Feedback Wall