Rabbit Anti-NPVF/RFRP antibody

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C7orf9; Neuropeptide NPSF; Neuropeptide NPVF; Neuropeptide RFRP-1; Neuropeptide RFRP-2; Neuropeptide RFRP-3; Neuropeptide VF; NPVF; RFRP; NPVF_HUMAN.

Cat:

SL19339R

Species Reactivity：

(predicted: Human,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human NPVF/RFRP:124-131/196

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]

Function:
Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced analgesia.

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is specifically expressed in the retina. Neuropeptides RFRP-1 and NPVF are detected in the hypothalamus.

Similarity:
Belongs to the FARP (FMRFamide related peptide) family.

SWISS:
Q9HCQ7

Gene ID:
64111

Database links:

Entrez Gene: 64111 Human

SwissProt: Q9HCQ7 Human

Unigene: 60473 Human

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