PRRG4 (Proline Rich And Gla Domain 4) is a Protein Coding gene. Diseases associated with PRRG4 include wagr syndrome. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is PRRG1.
Function:
GenomeRNAi human phenotypes for PRRG4:
Increased vaccinia virus (VACV) infection Mildly decreased CFP-tsO45G cell surface transport Decreased viability in esophageal squamous lineage Increased shRNA abundance (Z-score > 2) Decreased shRNA abundance (Z-score < -2)
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed in lung, liver, kidney, pancreas and placenta.
Post-translational modifications:
Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.
Similarity:
Contains 1 Gla (gamma-carboxy-glutamate) domain.
SWISS:
Q9BZD6
Gene ID:
79056
Database links:
Entrez Gene: 79056 Human
Entrez Gene: 228413 Mouse
Entrez Gene: 167336 Rat
Entrez Gene: 499847 Rat
Omim: 611690 Human
SwissProt: Q9BZD6 Human
SwissProt: Q8BGN6 Mouse
Unigene: 471695 Human
Unigene: 259609 Mouse
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