Rabbit Anti-NT5C/dNT1 antibody

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3''-pyrimidine nucleotidase; 5' nucleotidase, deoxy (pyrimidine); 5' nucleotidase, deoxy (pyrimidine), cytosolic type C; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, cytosolic type; 5', 3'-nucleotidase, cytosolic; 5-prime,3-prime-nu

Cat:

SL19486R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human NT5C/dNT1:101-201/201

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

Function:
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in skeletal muscle, heart and pancreas.

Similarity:
Belongs to the 5'(3')-deoxyribonucleotidase family.

SWISS:
Q8TCD5

Gene ID:
30833

Database links:

Entrez Gene: 30833 Human

Omim: 191720 Human

SwissProt: Q8TCD5 Human

Unigene: 67201 Human

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