This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]
Function:
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.
Similarity:
Belongs to the 5'-nucleotidase type 3 family.
SWISS:
Q96P26
Gene ID:
100526794
Database links:
Entrez Gene: 100526794 Human
Entrez Gene: 93034 Human
Entrez Gene: 70881 Mouse
Omim: 610526 Human
SwissProt: Q96P26 Human
SwissProt: Q91YE9 Mouse
Unigene: 120319 Human
Unigene: 272843 Mouse
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