This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Location:
Nucleus > nucleolus.
Similarity:
Belongs to the NOP14 family.
SWISS:
P78316
Gene ID:
8602
Database links:
Entrez Gene: 471124 Chimpanzee
Entrez Gene: 101146604 Gorilla
Entrez Gene: 8602 Human
Entrez Gene: 100441032 Orangutan
GenBank: BC026035 Human
GenBank: NP_003694.1 Human
Omim: 611526 Human
SwissProt: P78316 Human
Unigene: 627133 Human
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