Rabbit Anti-NUDT14 antibody

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Nucleoside diphosphate linked moiety X type motif 14; Nucleoside diphosphate-linked moiety X motif 14; NUD14_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 14; Nudix motif 14; NUDT14; UDP sugar diphosphatase; UDPG pyrophosphatase;

Cat:

SL19511R

Species Reactivity：

Human,(predicted: Mouse,Rat,Cow,Horse,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human NUDT14:1-100/222

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lane 1: A549 (Human) Cell Lysate at 30 ugLane 2: U87MG (Human) Cell Lysate at 30 ugPrimary: Anti- NUDT14 (SL19511R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 24 kDObserved band size: 25 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 is a UDPG pyrophosphatase (EC 3.6.1.45) that hydrolyzes UDPG to produce glucose 1-phosphate and UMP (Yagi et al., 2003 [PubMed 12429023]).[supplied by OMIM, Mar 2008]

Function:
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the Nudix hydrolase family.
Contains 1 nudix hydrolase domain.

SWISS:
O95848

Gene ID:
256281

Database links:

Entrez Gene: 100126049 Cow

Entrez Gene: 256281 Human

Entrez Gene: 66174 Mouse

Entrez Gene: 299346 Rat

Omim: 609219 Human

SwissProt: Q05B60 Cow

SwissProt: O95848 Human

SwissProt: Q9D142 Mouse

Unigene: 526432 Human

Unigene: 7070 Mouse

Picture

Sample:
Lane 1: A549 (Human) Cell Lysate at 30 ug
Lane 2: U87MG (Human) Cell Lysate at 30 ug
Primary:
Anti- NUDT14 (SL19511R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kD
Observed band size: 25 kD

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