Home > Product > Antibody > Rabbit Anti-SDS3 antibody
2400003N08Rik; 2410008L21Rik; 45 kDa Sin3 associated polypeptide; 45 kDa Sin3-associated polypeptide; AU067672; FLJ00052; FLJ13739; MGC104711; mSds3; RGD1305986; SAP45; SDS3; SDS3, yeast, homolog of; SDS3_HUMAN; Sin3 histone deacetylase core
Cat:
SL19606R
Species Reactivity:
(predicted: Human,Mouse,Cow,Monkey,)
Immunogen:
KLH conjugated synthetic peptide derived from human SDS3:251-328/328
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 1272884]).[supplied by OMIM, Mar 2008]

Function:
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.

Tissue Specificity:
Expressed in various cancer cell ines.

Similarity:
Belongs to the SDS3 family.

SWISS:
Q9H7L9

Gene ID:
64426

Database links:

Entrez Gene: 64426 Human

Entrez Gene: 71954 Mouse

Entrez Gene: 445099 Zebrafish

Omim: 608250 Human

SwissProt: Q9H7L9 Human

SwissProt: Q8BR65 Mouse

Unigene: 416630 Human

Unigene: 602312 Human

Unigene: 34456 Mouse



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