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Rabbit Anti-SEC24C antibody
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Function:
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Subcellular Location:
Cytoplasm. Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
SWISS:
P53992
Gene ID:
9632
Database links:
Entrez Gene: 9632 Human
Omim: 607185 Human
SwissProt: P53992 Human
Unigene: 81964 Human
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