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Home > Product > Antibody > Rabbit Anti-SEC62 antibody
Dtrp1; FLJ32803; hTP-1; HTP1; Membrane protein SEC62, S.cerevisiae, homolog of; OTTHUMP00000213390; sec62; SEC62 homolog (S. cerevisiae); SEC62_HUMAN; TLOC1; TP-1; Translocation protein 1; Translocation protein sec62.
Cat:
SL19619R
Species Reactivity：
Human,Mouse,Rat,(predicted: Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human SEC62:251-350/399
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: Lane 1: Thymus (Mouse) Lysate at 40 ugLane 2: Uterus (Mouse) Lysate at 40 ugLane 3: Thymus (Rat) Lysate at 40 ugLane 4: A431 (Human) Cell Lysate at 30 ugPrimary: Anti- SEC62 (SL19619R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 46 kDObserved band size: 48 kD
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Price: $
Product PDFs
Datasheet:


The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Function:
Required for preprotein translocation.

Subunit:
Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the SEC62 family.

SWISS:
Q99442

Gene ID:
7095

Database links:

Entrez Gene: 7095 Human

Entrez Gene: 69276 Mouse

Entrez Gene: 294912 Rat

Omim: 602173 Human

SwissProt: Q99442 Human

SwissProt: Q8BU14 Mouse

Unigene: 592561 Human



Picture

Sample:
Lane 1: Thymus (Mouse) Lysate at 40 ug
Lane 2: Uterus (Mouse) Lysate at 40 ug
Lane 3: Thymus (Rat) Lysate at 40 ug
Lane 4: A431 (Human) Cell Lysate at 30 ug
Primary: Anti- SEC62 (SL19619R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 48 kD
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