Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]
Function:
Protein transport. Probably involved in vesicular traffic.
Subcellular Location:
Cell membrane. Early endosome membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
SWISS:
P51148
Gene ID:
5878
Database links:
Entrez Gene: 5878 Human
Entrez Gene: 19345 Mouse
Entrez Gene: 287709 Rat
Omim: 604037 Human
SwissProt: P51148 Human
SwissProt: P35278 Mouse
Unigene: 650382 Human
Unigene: 29829 Mouse
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