The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq, Jul 2008]
Subcellular Location:
Nucleus.
Similarity:
Contains 2 RRM (RNA recognition motif) domains.
SWISS:
Q15434
Gene ID:
5939
Database links:
Entrez Gene: 5939 Human
Omim: 602387 Human
SwissProt: Q15434 Human
Unigene: 505729 Human
Unigene: 68372 Human
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