Rabbit Anti-RBMXL2 antibody

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Heterogeneous nuclear ribonucleoprotein G T; hnRNP G T; hnRNP G-T; HNRNPG T; HNRNPGT; HNRPGT; RBMX L2; RBMXL 2; RBMXL2; RMXL2_HUMAN; RNA binding motif protein X linked like 2; RNA-binding motif protein; Testes specific heterogenous nuclear rib

Cat:

SL19779R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human RBMXL2:221-320/392

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed predominantly in spermatocytes and less in round spermatids (at protein level). Expressed in germ cells.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
O75526

Gene ID:
27288

Database links:

Entrez Gene: 27288 Human

Entrez Gene: 76572 Mouse

Entrez Gene: 365344 Rat

Omim: 605444 Human

SwissProt: O75526 Human

Unigene: 121605 Human

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