This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2013]
Function:
Does not seem to be involved in anion transport.
Subunit:
Interacts (via SLCterminal domain) with PDZK1 (via SLCterminal PDZ domain); the interaction induces chloride and oxalate exchange transport
Subcellular Location:
Membrane.
Tissue Specificity:
Ubiquitous. Highest levels in kidney and pancreas. Lower expression in heart, skeletal muscle, liver and placenta. Also found in lung and brain.
Similarity:
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Contains 1 STAS domain.
SWISS:
Q9BXS9
Gene ID:
65010
Database links:
Entrez Gene: 65010 Human
Entrez Gene: 171429 Mouse
Entrez Gene: 497236 Pig
Entrez Gene: 301010 Rat
Omim: 610068 Human
SwissProt: Q9BXS9 Human
Unigene: 631925 Human
Unigene: 66648 Human
Unigene: 45201 Mouse
Unigene: 18851 Rat
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