Rabbit Anti-Relaxin 2 antibody

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H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; REL2_HUMAN; Relaxin 2 (H2); Relaxin 2; Relaxin A chain; Relaxin H2; Relaxin, Ovarian, Of Pregnancy; RLN2; RLXH2.

Cat:

SL19835R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human Relaxin 2:101-185/185

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]

Function:
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary.

Similarity:
Belongs to the insulin family.

SWISS:
P0968

Gene ID:
6013

Database links:

Entrez Gene: 6013 Human

Entrez Gene: 6019 Human

Entrez Gene: 25616 Rat

Omim: 179740 Human

SwissProt: P04090 Human

SwissProt: P0968 Human

SwissProt: P47932 Mouse

SwissProt: P01347 Rat

Unigene: 127032 Human

Unigene: 368996 Human

Unigene: 5033 Mouse

Unigene: 9830 Rat

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