The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly. [provided by RefSeq, Oct 2009]
Function:
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular Location:
Golgi apparatus membrane.
Similarity:
Belongs to the RER1 family.
SWISS:
O15258
Gene ID:
11079
Database links:
Entrez Gene: 100125922 Cow
Entrez Gene: 11079 Human
Entrez Gene: 67830 Mouse
Entrez Gene: 298675 Rat
SwissProt: A5PJ65 Cow
SwissProt: O15258 Human
SwissProt: Q9CQU3 Mouse
SwissProt: Q498C8 Rat
Unigene: 591454 Human
Unigene: 241604 Mouse
Unigene: 129142 Rat
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