Rabbit Anti-phospho-RGS16 (Tyr168) antibody

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RGS16 (phospho Y168); p-RGS16 (phospho Y168); A28 RGS14; A28 RGS14P; A28-RGS14P; HGNC:9997; hRGS-r; OTTHUMP00000033147; Regulator of G protein signaling 16; Regulator of G protein signalling 16; Regulator of G-protein signaling 16; Retinal-specif

Cat:

SL19856R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,)

Immunogen：

KLH conjugated synthesised phosphopeptide derived from human RGS16 around the phosphorylation site of Tyr168:DS(p-Y)PR

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $256.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.

Tissue Specificity:
Abundantly expressed in retina with lower levels of expression in most other tissues.

Post-translational modifications:
Palmitoylated on Cys-2 and/or Cys-12.
Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.

Similarity:
Contains 1 RGS domain.

SWISS:
O15492

Gene ID:
6004

Database links:

Entrez Gene: 6004 Human

Entrez Gene: 19734 Mouse

Omim: 602514 Human

SwissProt: O15492 Human

SwissProt: P97428 Mouse

Unigene: 413297 Human

Unigene: 181709 Mouse

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