Rabbit Anti-RGS8 antibody | Sunlong Medical

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Regulator of G Protein Signalling 8; Regulator of G-protein signaling 8; RGS8; RGS8_HUMAN.

Cat:

SL19864R

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human RGS8:1-100/180

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 RGS domain.

SWISS:
P57771

Gene ID:
85397

Database links:

Entrez Gene: 85397 Human

Entrez Gene: 67792 Mouse

Entrez Gene: 54297 Rat

Omim: 607189 Human

SwissProt: P57771 Human

SwissProt: Q8BXT1 Mouse

SwissProt: P41964 Rat

Unigene: 20982 Human

Unigene: 458417 Human

Unigene: 379143 Mouse

Unigene: 89634 Rat

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