Home
>
Product
>
Antibody
>
Rabbit Anti-PPFIA4 antibody
PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008]
Function:
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Subcellular Location:
Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
Tissue Specificity:
Expressed only in the heart, brain, and skeletal muscle.
Similarity:
Belongs to the liprin family. Liprin-alpha subfamily.
Contains 3 SAM (sterile alpha motif) domains.
SWISS:
O75335
Gene ID:
8497
Database links:
Entrez Gene: 8497 Human
Entrez Gene: 68507 Mouse
Entrez Gene: 140592 Rat
Omim: 603145 Human
SwissProt: O75335 Human
SwissProt: Q91Z80 Rat
Unigene: 153648 Human
Unigene: 105913 Rat
|
|