This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.[provided by RefSeq, Oct 2009]
Function:
This protein is associated with snRNP U1.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the U1 small nuclear ribonucleoprotein C family.
Contains 1 matrin-type zinc finger.
SWISS:
P09234
Gene ID:
6631
Database links:
Entrez Gene: 419901 Chicken
Entrez Gene: 747404 Chimpanzee
Entrez Gene: 614553 Cow
Entrez Gene: 608109 Dog
Entrez Gene: 101136854 Gorilla
Entrez Gene: 6631 Human
Entrez Gene: 20630 MouseEntrez Gene: 100441168 Orangutan
Entrez Gene: 10015926 Pig
Entrez Gene: 36368 Rat
Entrez Gene: 712667 Rhesus monkey
Entrez Gene: 100225930 Zebra finch
GenBank: NP_003081.2 Human
Omim: 603522 Human
SwissProt: E1C6F0 Chicken
SwissProt: Q32PA0 Cow
SwissProt: E2RGI3 Dog
SwissProt: P09234 Human
SwissProt: Q62241 Mouse
SwissProt: F6TFD9 Rhesus monkey
Unigene: 1063 Human
Unigene: 103949 Mouse
Unigene: 308514 Mouse
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