VOPP1 (Vesicular, Overexpressed In Cancer, Prosurvival Protein 1) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity.
Function:
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
Subcellular Location:
Cytoplasmic vesicle membrane. When overexpressed, localizes in the nucleus and perinuclear regions.
Tissue Specificity:
Widely expressed with highest levels in thymus and ovary.
Similarity:
Belongs to the VOPP1/ECOP family.
SWISS:
Q96AW1
Gene ID:
81552
Database links:
Entrez Gene: 767861 Cow
Entrez Gene: 81552 Human
Entrez Gene: 26423 Mouse
Entrez Gene: 362374 Rat
Omim: 611915 Human
SwissProt: A6QNZ8 Cow
SwissProt: Q96AW1 Human
SwissProt: Q8R1C3 Mouse
SwissProt: Q5RDG5 Orangutan
SwissProt: B5DEK8 Rat
Unigene: 488307 Human
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