Rabbit Anti-ZNF769/RB associated KRAB repressor antibody

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RB associated KRAB repressor; hRBaK; Hypothetical protein RBAK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger protein; RBAK; RBAK_HUMAN; Zinc finger protein 769; ZNF 769; ZNF769.

Cat:

SL4381R

Species Reactivity：

(predicted: Human,Mouse,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF769:251-350/714

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

Function:
May repress E2F-dependent transcription. May promote AR-dependent transcription.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 16 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
Q9NYW8

Gene ID:
57786

Database links:

Entrez Gene: 57786 Human

Entrez Gene: 57782 Mouse

Omim: 608191 Mouse

SwissProt: Q9NYW8 Human

SwissProt: Q8BQC8 Mouse

Unigene: 396178 Human

Unigene: 64419 Mouse

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