Rabbit Anti-RBMY1A1 antibody

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hRBMY; MGC181956; RBM1; RBM2; RBMY; RNA binding motif protein 1; RNA binding motif protein 2; RNA binding motif protein Y chromosome family 1 member A1; RNA binding motif protein Y chromosome family 1 member A1/C; RNA binding motif protein Y chromosome fa

Cat:

SL10923R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human RBMY1A1:81-180/496

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the SLCterminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]

Function:
RBMY1A1 is an RNA-binding protein which may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre-mRNA splicing in the testis.

Subunit:
Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3.

Subcellular Location:
Nuclear.

Tissue Specificity:
Testis-specific.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
P0DJD3

Gene ID:
5940

Database links:

Entrez Gene: 5940 Human

Omim: 80006 Human

SwissProt: P0DJD3 Human

Unigene: 380450 Human

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