The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins. [provided by RefSeq, Jul 2008]
Tissue Specificity:
Expressed in the hair follicles.
Similarity:
Belongs to the intermediate filament family.
SWISS:
Q9NSB2
Gene ID:
3890
Database links:
Entrez Gene: 3890 Human
Entrez Gene: 16136 Mouse
Entrez Gene: 31564 Rat
Omim: 602766 Human
SwissProt: Q9NSB2 Human
SwissProt: Q99M73 Mouse
Unigene: 272336 Human
Unigene: 25292 Mouse
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