Rabbit Anti-RAB11FIP1 antibody

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FLJ22524; FLJ22622; HGNC:30265; MGC78448; No Rab11 binding protein 1A; NOEL1A; Rab coupling protein; Rab effector protein; Rab interacting recycling protein; Rab-coupling protein; RAB11 family interacting protein 1 (class I); Rab11 family inter

Cat:

SL21126R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human RAB11FIP1:1101-1200/1283

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]

Function:
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.

Subcellular Location:
Recycling endosome. Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC) and Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).

Tissue Specificity:
Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine.

Similarity:
Contains 1 C2 domain.
Contains 1 FIP-RBD domain.

SWISS:
Q6WKZ4

Gene ID:
80223

Database links:

Entrez Gene: 80223 Human

Entrez Gene: 75767 Mouse

Entrez Gene: 498650 Rat

Omim: 608737 Human

SwissProt: Q6WKZ4 Human

SwissProt: Q9D620 Mouse

SwissProt: Q3B7T9 Rat

Unigene: 191179 Human

Unigene: 205335 Mouse

Unigene: 49288 Rat

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