Home
>
Product
>
Antibody
>
Rabbit Anti-SLC25A17 antibody
This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Function:
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'-diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter-exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro.
Subcellular Location:
Cytoplasm. Peroxisome membrane.
Tissue Specificity:
Ubiquitous. Expressed in liver.
Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
SWISS:
O8768
Gene ID:
10478
Database links:
Entrez Gene: 10478 Human
Entrez Gene: 300083 Rat
Omim: 606795 Human
SwissProt: O8768 Human
Unigene: 474938 Human
Unigene: 94733 Rat
|
|