Rabbit Anti-SLC30A4 antibody

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Dri 27 protein; Lethal milk protein; Slc30a4; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4; Znt4; ZNT4_HUMAN.

Cat:

SL21253R

Species Reactivity：

Mouse,(predicted: Human,Rat,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human SLC30A4:1-100/429<Cytoplasmic>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]

Function:
Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.

Subcellular Location:
Endosome membrane.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
SLC30A subfamily.

SWISS:
O14863

Gene ID:
7782

Database links:

Entrez Gene: 7782 Human

Omim: 602095 Human

SwissProt: O14863 Human

Unigene: 162989 Human

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