Rabbit Anti-Nucleoplasmin 2 antibody

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NPM2; NPM2_MOUSE; nucleophosmin/nucleoplasmin, 2; nucleoplasmin 2; Nucleoplasmin-2.

Cat:

SL24104R

Species Reactivity：

(predicted: Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from mouse Nucleoplasmin 2:121-207/207

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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NPM2 (Nucleophosmin/Nucleoplasmin 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and enzyme binding. An important paralog of this gene is NPM1.

Function:
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.

Subunit:
Homopentamer, when bound to H2A-H2B dimers only. Homodecamer of two stacked pentamers, when bound to H2A-H2B dimers and H3-H4 tetramers simultaneously (By similarity).

Subcellular Location:
Nucleus. Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.

Similarity:
Belongs to the nucleoplasmin family.

SWISS:
Q80W85

Gene ID:
32888

Database links:

Entrez Gene: 10361 Human

Entrez Gene: 32888 Mouse

Omim: 608073 Human

SwissProt: Q86SE8 Human

SwissProt: Q80W85 Mouse

Unigene: 131055 Human

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