POU5F2 (POU Domain Class 5, Transcription Factor 2) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is POU5F1.
Function:
Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By similarity).
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in skeletal and cardiac muscles, brain, heart and lung. Little or no detectable expression found in pancreas, kidney, liver or placenta.
Similarity:
Belongs to the POU transcription factor family.
Class-5 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.
SWISS:
Q9DAC9
Gene ID:
75507
Database links:
Entrez Gene: 134187 Human
Entrez Gene: 75507 Mouse
SwissProt: Q8N7G0 Human
SwissProt: Q9DAC9 Mouse
Unigene: 678995 Human
Unigene: 443255 Mouse
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