This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Function:
Potential calcium-dependent cell-adhesion protein.
Subcellular Location:
Cell membrane.
Similarity:
Contains 7 cadherin domains.
SWISS:
Q9HC56
Gene ID:
5101
Database links:
Entrez Gene: 5101 Human
Omim: 603581 Human
SwissProt: Q9HC56 Human
Unigene: 654709 Human
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