Home > Product > Antibody > Rabbit Anti-PAF1 antibody
F23149 1; FLJ11123; hPAF1; PAF 1; PAF1; Paf1 RNA polymerase II associated factor homolog; PAF1_HUMAN; Pancreatic differentiation protein 2; PD 2; PD2; PD2 protein; RNA polymerase II associated factor homolog; RNA polymerase II-associated facto
Cat:
SL21001R
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human PAF1:251-350/531
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Function:
The mammalian PAF1 complex is a multifunctional complex. The PAF1 complex interacts with RNA polymerase II and may be involved in both initiation and elongation, and in histone methylation and RNA processing. Has oncogenic activity in vivo and in vitro.

Subcellular Location:
Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin.

Similarity:
Belongs to the PAF1 family.

SWISS:
Q8N7H5

Gene ID:
54623

Database links:

Entrez Gene: 54623 Human

Entrez Gene: 54624 Mouse

Entrez Gene: 361531 Rat

Entrez Gene: 446278 Xenopus laevis

Omim: 610506 Human

SwissProt: Q8N7H5 Human

SwissProt: Q8K2T8 Mouse

SwissProt: Q4V886 Rat

SwissProt: A2BD83 Xenopus laevis

Unigene: 466714 Human

Unigene: 7916 Mouse

Unigene: 161558 Rat

Unigene: 29705 Xenopus laevis



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