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Rabbit Anti-PPFIBP2 antibody
This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Function:
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the liprin family.
Liprin-beta subfamily.
Contains 3 SAM (sterile alpha motif) domains.
SWISS:
Q8ND30
Gene ID:
8495
Database links:
Entrez Gene: 8495 Human
Entrez Gene: 19024 Mouse
Entrez Gene: 308918 Rat
Omim: 603142 Human
SwissProt: Q8ND30 Human
SwissProt: O35711 Mouse
Unigene: 655714 Human
Unigene: 2817 Mouse
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