Rabbit Anti-p39/CDK5R2 antibody

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CD5R2_HUMAN; CDK5 activator 2; Cdk5r2; Cyclin dependent kinase 5 activator 2; Cyclin dependent kinase 5 regulatory subunit 2; Cyclin-dependent kinase 5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; NCK5AI; p39; P39I; p39nck5ai.

Cat:

SL21065R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human p39/CDK5R2:251-350/367

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]

Function:
Activator of CDK5/TPKII.

Subunit:
Heterodimer of a catalytic subunit and a regulatory subunit.

Tissue Specificity:
Brain and neuron specific.

Post-translational modifications:
Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39).

Similarity:
Belongs to the cyclin-dependent kinase 5 activator family.

SWISS:
Q13319

Gene ID:
21065

Database links:

Entrez Gene: 8941 Human

Entrez Gene: 12570 Mouse

Omim: 603764 Human

SwissProt: Q13319 Human

SwissProt: O35926 Mouse

Unigene: 15892 Human

Unigene: 153833 Mouse

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